论文部分内容阅读
各地试验证明,甲氟喹治疗成人抗氯喹恶性疟效果很好,但对儿童疗效很少报道。泰国恶性疟原虫对氯喹和磺胺多辛/乙氨嘧啶均有高度抗性,对奎宁也有抗性。本文报告泰国用甲氟喹治疗儿童抗氯喹恶性疟的效果及其安全性。 1982年1月至1984年7月,选择5～12岁恶性疟现症病例,在曼谷麦希伦大学热带医学学院热带病医院住院治疗,重症、夹杂症或不能口服的病人不作为观察对象。服药当天(Do)记录症状、体重和身高,每12小时检
Tests throughout the trial proved that mefloquine is very effective in treating adults resistant to chloroquine and falciparum malaria, but the efficacy in children is seldom reported. Plasmodium falciparum in Thailand is highly resistant to chloroquine and sulfadoxine / pyrimethamine, as well as to quinine. This article reports on the efficacy and safety of mefloquine in the treatment of children resistant to chloroquine falciparum malaria in Thailand. From January 1982 to July 1984, cases of falciparum malaria cases between 5 and 12 years old were selected for treatment of patients with severe, obstructive or oral incontinence at the Tropical Hospital of Medicine, Tropical Medicine College, University of Maehara, Bangkok. On the day of medication (Do) record symptoms, weight and height, seized every 12 hours