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Shiinas 等报道了77例肝细胞癌108个病灶的419次经皮穿刺注射无水酒精治疗(PEIT)的经验。患者年龄39～82岁。73例原发性肝细胞癌伴有不同程度的肝硬化,4例原发性肝细胞癌并慢性肝炎。所有病例均由细针穿刺活检诊断。每次向病灶注入99.5%的无水酒精2～8ml,每周注射2～3次,直到注入的酒精达预计量。根治组的无水酒精总量按如下公式计算:V=4/3π(r+0.5)~3。V(ml)为注射总量,r(cm)是病灶半径,半径加0.5(cm)以提供一个安全界限。注射无水酒精治疗后,14例患者做了病理组织学检查,其中10例肿瘤完全坏死,3例90%
Shiinas et al. Reported the experience of 419 percutaneous punctate injections of anhydrous alcohol (PEIT) on 77 lesions of hepatocellular carcinoma in 108 lesions. Patients aged 39 to 82 years old. 73 cases of primary hepatocellular carcinoma with varying degrees of cirrhosis, 4 cases of primary hepatocellular carcinoma and chronic hepatitis. All cases were diagnosed by fine needle aspiration biopsy. Each injection of 99.5% ethanol into the lesion 2 ~ 8ml, injection 2 to 3 times a week until the amount of alcohol injection expected. The total amount of anhydrous ethanol in the radical group was calculated as follows: V = 4 / 3π (r + 0.5) ~ 3. V (ml) is the total amount injected, r (cm) is the radius of the lesion and the radius plus 0.5 (cm) provides a safety margin. Fourteen patients underwent histopathological examination after injection of anhydrous alcohol, of which 10 had complete necrosis and 3 had 90%