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采用免疫组化方法检测了31例进展期胃癌新鲜标本中E－CD蛋白表达以及患者术前血清中CEA水平，分析了它们与胃癌转移的关系。结果：胃癌标本中E－CD表达与胃癌分化程度、Borrmann分型、胃周淋巴结转移、腹膜播散有关；血清CEA阳性车与肿瘤体积大小、血行昨转移、腹膜播散有关。腹腔游离癌细胞与E－CD和血清CEA阳性年均有关。提示：E－CD低表达或缺失以及血清CEA升高与胃癌转移密切相关。
Immunohistochemistry was used to detect the expression of E-CD protein in 31 specimens of advanced gastric cancer and the CEA levels in the preoperative serum. The relationship between them and the metastasis of gastric cancer was analyzed. Results: The expression of E-CD in gastric cancer specimens was related to the degree of gastric cancer differentiation, Borrmann type, lymph node metastasis and peritoneal dissemination. The serum CEA positive car was related to the size of tumors, metastasis of blood and peritoneal dissemination. Peritoneal free cancer cells were positively correlated with E-CD and serum CEA. Tip: The low expression or absence of E-CD and elevated serum CEA are closely related to the metastasis of gastric cancer.