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性激素结合球蛋白(SHBG)是血浆中与雄激素及雌激素有高亲和力的性激素转运蛋白,SHBG与前列腺的生理作用及良性前列腺增生(BPH)有关。文献报道大荨麻(Urticadioica)根中的极性提取物可用于BPH的治疗,并确定活性成分为木脂类,为此进一步研究了木脂类与SHBG的亲和作用。
Sex Hormone Binding Globulin (SHBG) is a high-affinity sex hormone transporter in plasma with androgens and estrogens. SHBG is related to the physiological effects of prostate and benign prostatic hyperplasia (BPH). It has been reported in the literature that polar extracts from roots of Urtica dinica can be used for the treatment of BPH and that the active ingredient is lignans. The affinity of lignans and SHBG has been further studied for this purpose.