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目的：在中医药理论指导下，以古方“延寿丹”为方源，研制具有抗衰延寿功效的保健药品、食品系列新产品。方法：应用现代药理及临床试验方法，将加减化裁的新方制剂与延寿丹原方制剂做对比实验研究，并对各产品的理论性质作全面分析检查。结果：新方制剂“回春口服液”具有明显抗疲劳、耐缺氧、抑制过氧化脂质形成，减少脂褐素，清除氧自由基的作用；尚能消除“阳虚”、“脾虚”动物模型的阳虚、脾虚症状，降低耐寒试验小鼠死亡率，提高小鼠学习记忆力；使果蝇平均寿命延长32.0％～55．8％。延寿丹原方制剂“延年益寿精”亦有相似的效果，但指标不及回春口服液全面。试验还显示，四种保健食品中药原汁也具有不同程度的抗衰延寿功效。临床对比观察冠心病人175例，结果表明，回春口服液能增强人体免疫功能，明显改善冠心病人头昏、耳鸣、心悸气短等十项症状，显效率57．0％;总有效率92.7％，显效率明显优于延年益寿精对照组（P＜0．01）。结论：延寿丹原方制剂及化裁新方制剂均具有增强体质，提高智力，延缓衰老的功效，但新方制剂效果优于原方制剂效果。
Purpose: Under the guidance of the theory of traditional Chinese medicine, with the ancient side “Yan Shou Dan” as the source, we will develop new series of health care products and food products that have the effect of prolonging life. Methods: Using modern pharmacology and clinical test methods, comparative experiments were conducted between the addition and subtraction of the new formula and the Yanshou Danyuan formula, and the theoretical properties of each product were comprehensively analyzed. Results: New prescription “rejuction oral liquid ” has obvious anti-fatigue, anti-anoxia, inhibit lipid peroxide formation, reduce lipofuscin, scavenging oxygen free radicals; can still eliminate “yang deficiency”, “Spleen deficiency” animal model of the symptoms of yang deficiency, spleen deficiency, reduce the mortality rate of cold-resistant mice, improve the learning and memory of mice; the average life span of fruit flies increased 32.0% to 55.8%. Yanshou Dan original formula “longevity ” has similar effects, but the indicators are less comprehensive than the rejuvenation oral liquid. The experiment also showed that the four kinds of health food Chinese herbal juice also have different degrees of anti-aging life. Clinical comparison observed 175 cases of coronary heart disease, the results show that Huichun oral liquid can enhance the body’s immune function, significantly improve the coronary heart disease, dizziness, tinnitus, palpitation, shortness of breath and other ten symptoms, significant efficiency of 57.0%; total efficiency of 92.7% Significantly better than the longevity control group (P <0.01). Conclusion: Both Yanshou Danyuan Formula and Xinfang Xinfang Formula have the effects of enhancing physical fitness, increasing intelligence, and delaying aging. However, the effect of Xinfang Formulation is better than that of the original formula.