【摘 要】
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Non-coding small RNAs,such as small interfering RNA (siRNA),microRNA (miRNA),and piwi-interacting RNA (piRNA),have a common feature that their sizes always fall
【机 构】
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Department of Endocrine, Shanghai Gongli Hospital, the Second Military Medical University, Shanghai
论文部分内容阅读
Non-coding small RNAs,such as small interfering RNA (siRNA),microRNA (miRNA),and piwi-interacting RNA (piRNA),have a common feature that their sizes always fall within a narrow,defined range of between 18 and 32 nt [1,2].These tiny RNAs have revolutionized our comprehension of gene expression as key posttranscriptional regulators.Compared with long RNA,small RNA has a low abundance with very small size,making it difficult to be detected using traditional methods [3].
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