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新药PF1022A是一种具有r—氨基丁酸(CABA)类作用的新驱蠕虫药,特别适用于治疗线虫感染。本文观察该药对大鼠休内广州管圆线虫的治疗作用。将感染20条幼虫的大鼠,于感染后11至15天,口服PF1002A10和20mg/kg/天和腹腔注射2.5mg/kg/天治疗,感染后第49天解剖,发现各治疗组和非治疗组大鼠寄生的数量大致相等,几乎是同一天各组大鼠的粪便中均出现幼虫,表明
The new drug, PF1022A, is a newly developed helminth drug with the class of r-aminobutyric acid (CABA) and is particularly suitable for the treatment of nematode infections. This article observed the drug treatment of Aconitum in Guangxi off-line treatment. Rats infected with 20 larvae were treated with oral PF1002A10 and 20 mg / kg / day orally and with an intraperitoneal injection of 2.5 mg / kg / day 11 to 15 days post infection, and dissected on the 49th day after infection and found that each treatment group and a non-treatment The number of parasites in the group of rats was roughly equal, and larvae appeared in the stools of almost all rats on the same day, indicating