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以高效液相色谱法测定青霉素G皮试液及浓储备液在低温下的稳定性,结果表明:青霉素G稀溶液较浓溶液稳定,溶液的pH值随放置时间的延长而降低,青霉素G的降解速率随pH的降低而加速。
The stability of penicillin G skin test solution and concentrated stock solution at low temperature was determined by high performance liquid chromatography. The results showed that the dilute solution of penicillin G was stable and the solution pH value decreased with the prolongation of storage time. Degradation rate increases with decreasing pH.