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研究红藻鸭毛藻的化学成分.采用溶剂提取和色谱分离技术进行化学成分分离,根据质谱和波谱数据鉴定化合物结构.从鸭毛藻提取物中分离得到17个化合物,分别鉴定为胆甾醇(1),3β,5β-二羟基-B-胆甾烷-6β-甲醛(2),6β-羟基-胆甾-4-烯-3-酮(3),1-O-肉豆蔻酰基-3-O-(6'-硫代-α-D-脱氧吡喃葡萄糖基)甘油(4),1-O-棕榈酰基-3-O-(6'-硫代-α-D-脱氧吡喃葡萄糖基)甘油(5),1-O-棕榈酰基-3-O-[α-D-吡喃半乳糖基(1→6)β-D-吡喃半乳糖基]甘油(6),1-O-棕榈酰基-3-O-β-D-吡喃半乳糖基甘油(7),棕榈酸甲酯(8),硬脂酸甲酯(9),棕榈酸(10),顺式乌头酸-γ-正丁酯(11),顺式乌头酸-α-正丁酯(12),苯乙胺(13),3,5-二溴-L-酪氨酸(14),异戊胺(15),焦谷氨酸甲酯(16),焦谷氨酸正丁酯(17).化合物1～17均首次从鸭毛藻属中分离得到,化合物7具有一定的醛糖还原酶抑制活性.“,”The extraction and solvent fractionation of red alga Symphyocladia latiuscula,and repeated column chromatography led to isolation of 17 compounds:cholesterol (1),3β,5β-dihydroxy-B-norcholestan-6β-carboxaldehyde (2),6β-hydroxy-cholest-4-ene-3-one (3),1-O-myristoyl-3-O-(6'-sulfo-α-D-quinovopyranosyl)glycerol (4),1-O-palmitoyl-3-O-(6'-sulfo-α-D-quinovopyranosyl) glycerol (5),1-O-palmitoyl-3-O-[α-D-galactopyranosyl(1→6)β-D-galactopyranosyl] glycerol (6),1-O-palmitoyl-3-O-β-D-galactopyranosylglycerol (7),methyl hexadecanoate (8),methyl stearate (9),hexadecanoic acid (10),γ-n-butyl cis-aconiate (11),a-n-Butyl cis-aconiate (12),phenethylarnine (13),3,5-dibromo-L-tyrosine (14),3-methylbutylamine (15),methyl pyroglutamate (16),n-butyl pyroglutamate (17).The structures of these compounds were identified by NMR spectroscopy and mass spectrometry,and compared with those reported in the literature.All the compounds were isolated from Symphyocladia genus for the first time.These compounds were investigated for their inhibitory effects on human recombinant aldose reductase in vitro.Of the compounds,1-O-palmitoyl-3-O-β-D-galactopyranosylglycerol (7) demonstrated moderate enzyme inhibition.