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胃泰胶囊对免疫及理化攻击等综合法所致的大鼠萎缩性胃炎模型有良好的治疗作用,动物一般状况改善,胃酸及消化酶活性升高,胃粘膜萎缩病变及炎症改善;并使水杨酸性胃炎病变减轻。对小鼠胃肠推进运动无影响;抑制二甲苯致小鼠耳壳肿胀及皮下棉球肉芽肿的增生,抑制醋酸引起的小鼠扭体反应,对热板法致痛无影响;增加大鼠的红细胞C3b受体花环率、淋巴细胞转化率和小鼠吞噬细胞的功能,升高血清IgG水平。主题词:@胃泰胶囊/药理学;萎缩性胃炎/中药疗法;动物疾病模型
Weitai capsule has a good therapeutic effect on atrophic gastritis model induced by immune and physicochemical attack. The general condition of animals is improved, gastric acid and digestive enzyme activity are increased, gastric mucosal atrophy lesions and inflammation are improved; Yang acid gastritis lesions reduced. No effect on gastrointestinal propulsion in mice; Suppression of murine ear shell swelling caused by xylene and proliferation of granuloma of subcutaneous tampon, inhibition of acetic acid-induced writhing in mice, no effect on pain caused by hot plate method; increase in rats The erythrocyte C3b receptor rosette rate, lymphocyte transformation rate, and mouse phagocyte function increased serum IgG levels. Subject Terms: @Weitai Capsule/Pharmacology;Atrophic gastritis/TCM therapy;Animal disease model