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宿主和病原体的关系对呼吸道感染的临床表现有很大影响,一方面血液恶性肿瘤、脏器移植、AIDS等会使宿主的免疫功能发生种种改变;另一方面病原体的耐药性、菌交替等可影响抗菌素的利用。长崎大学第二内科比较了1975～79年和1986～90年两个五年间晚期肺炎的菌群发现,革兰氏阴性杆菌(主要是大肠、肺炎杆菌、流感嗜血杆菌)有明显减少,而革兰氏阳性球菌(主要是金葡菌、肠球菌)有
The relationship between the host and the pathogen has a great impact on the clinical manifestations of respiratory infections. On the one hand, hematological malignancies, organ transplantation, AIDS, etc. will make various changes in the immune function of the host; on the other hand, Can affect the use of antibiotics. The Second Internal Medicine Division of Nagasaki University compared the bacterial population of advanced pneumonia in two years between 1975 and 1979 and 1986 to 1990. Gram-negative bacilli (mainly large intestine, Klebsiella pneumoniae and Haemophilus influenzae) were significantly reduced, Gram-positive cocci (mainly Staphylococcus aureus, enterococci) there