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哮喘是患者急诊入院的首要原因,主要用喷雾法给予舒喘灵进行治疗,而通过剂量计吸入给药则常用于门诊的维持治疗.本研究通过随机、双盲、对照试验证实,用带腔的剂量吸入计吸入舒喘灵与喷雾给药疗效相同,且能使药物更迅速地到达作用部位。患者与方法入急诊室的严重哮喘患者,除外:年龄<8岁或>45岁;有心绞痛、呼衰或COPD 史;不能完成肺量计操作;吸烟史超过10年。入选者35例,于治疗前测脉率、呼吸频率、口腔温度、血压、血清茶碱水平、血钾和血糖,以及FEV_1、FVC 和PEFR.将患者随机分为两组,双盲法给药.20例(喷雾组)用带腔的剂量计吸入安慰剂后立即用喷雾器给舒
Asthma is the leading cause of emergency hospital admission and is mainly treated with salbutamol by the spray method, while it is often used in outpatient maintenance treatment by inhalation by a dosimeter.This study was confirmed by randomized, double-blind, The inhaler inhaled salbutamol administered in the same dose as the nebulized dose and allowed the drug to reach the site of action more rapidly. PATIENTS AND METHODS Severe asthma patients admitted to the emergency room except for age <8 years or> 45 years; angina, respiratory failure or history of COPD; failed to complete spirometry; smoking history> 10 years. Thirty-five patients were enrolled in the study, and their pulse rate, respiratory rate, oral temperature, blood pressure, serum theophylline level, serum potassium and blood glucose, and FEV_1, FVC and PEFR were measured before treatment. .20 cases (spray group) with a cavity of the dosimeter inhalation of placebo immediately after the sprayer to Shu