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目的观察琥珀酸氢考治疗肺炎支原体(MP)感染伴哮喘发作患儿的疗效。方法 MP感染伴哮喘发作患儿120例,随机均分为治疗组和对照组,治疗组予琥珀酸氢考5mg/kg,每日1次,静脉点滴。两组患儿均加用抗生素及氨茶碱治疗,7-10d后观察两组临床疗效及治疗前后血清IgE水平。结果治疗组血清IgE水平下降率高于对照组(86.7%vs.51.7%)(P<0.05)。治疗组总有效率高于对照组(91.7%vs.63.3%)(P<0.05)。结论琥珀酸氢考治疗MP感染伴哮喘发作患儿临床疗效可靠。
Objective To observe the efficacy of hydrogen succinate in the treatment of Mycoplasma pneumoniae (MP) infection in children with asthma attack. Methods 120 children with MP infection and asthma attack were randomly divided into treatment group and control group. Hydrogen succinate test was given in the treatment group to 5 mg / kg once daily by intravenous drip. Both groups were treated with antibiotics and aminophylline. After 7-10 days, the clinical efficacy and serum IgE level were observed before and after treatment. Results The decrease rate of serum IgE level in the treatment group was higher than that in the control group (86.7% vs.51.7%, P <0.05). The total effective rate in the treatment group was higher than that in the control group (91.7% vs.63.3%) (P <0.05). Conclusion Hydrogen succinate test in children with MP infection and asthma attack clinical efficacy is reliable.