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目的探讨吸入布地奈德福莫特罗干粉联合口服槐杞黄颗粒治疗对支气管哮喘患儿的效果。方法选择6-12岁哮喘患儿54例,分为A组28例,B组26例。两组均给予布地奈德福莫特罗干粉吸入治疗,A组另加用槐杞黄颗粒口服。治疗1、3个月后测定第1秒用力呼气量占预测值百分比(FEV1%)、呼气峰流速占预测值百分比(PEF%)及呼出气一氧化氮(FeNO)值;比较两组日、夜间临床症状评分。结果两组治疗后FEV1%、PEF%、FeNO值均较治疗前有改善(P<0.05);治疗1个月后,A组FEV1、PEF%上升及FeNO值降低更明显,与B组比较差异有统计学意义(P<0.05);A组日间临床症状评分低于B组(P<0.05)。结论吸入布地奈德福莫特罗联用口服槐杞黄比单用布地奈德福莫特罗,可以更大程度改善哮喘儿童肺功能及临床症状。
Objective To investigate the effect of inhaled budesonide formoterol powder combined with oral Huai Qi Huang granules on bronchial asthma in children. Methods 54 asthmatic children aged 6-12 years were divided into group A (28 cases) and group B (26 cases). Both groups were given budesonide formoterol dry powder inhalation therapy, group A plus Huai Qi Huang particles orally. After 1 and 3 months of treatment, the forced expiratory volume per second (FEV1%), the percentage of predicted peak expiratory flow (PEF%) and exhaled nitric oxide (FeNO) were measured. Day and night clinical symptom score. Results The FEV1%, PEF% and FeNO values in both groups were significantly improved after treatment (P <0.05). After 1 month of treatment, the increase of FEV1 and PEF% and the decrease of FeNO in group A were more obvious than those in group B (P <0.05). The score of clinical symptoms in group A was lower than that in group B (P <0.05). Conclusion Inhaled budesonide formoterol combined with oral Huaiqi yellow than budesonide formoterol can improve pulmonary function and clinical symptoms of asthmatic children to a greater extent.