银杏叶注射液治疗老年急性脑梗死的临床观察

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目的:探讨银杏叶注射液治疗老年急性脑梗死的临床疗效。方法:选择我院符合诊断标准的老年急性脑梗死患者80例,随机分为治疗组与对照组各40例。对照组予常规治疗,治疗组在对照组基础上加用银杏叶注射液治疗。治疗2周后比较两组患者的临床疗效,3个月后比较两组患者的血液流变学、动脉粥样硬化变化情况。结果:治疗组总有效率为95.0%,优于对照组的87.5%(P<0.05);治疗第1、2周后,治疗组神经功能缺损评分均低于对照组(P<0.05);治疗后3个月,治疗组的Fbg、红细胞比容、红细胞聚集指数、全血高切黏度以及全血低切黏度水平均低于对照组(P<0.05);治疗组斑块厚度、斑块长径及IMT均低于对照组(P<0.05)。结论:银杏叶注射液治疗老年急性脑梗死有较好的临床疗效,能改善患者的动脉粥样硬化程度及血液流变学指标水平。 Objective: To investigate the clinical efficacy of Ginkgo biloba injection in the treatment of senile acute cerebral infarction. Methods: Eighty elderly patients with acute cerebral infarction who meet the diagnostic criteria were randomly divided into treatment group (40 cases) and control group (40 cases). The control group was given routine treatment. The treatment group was treated with Ginkgo biloba injection on the basis of the control group. After 2 weeks of treatment, the clinical efficacy of the two groups was compared. After three months, the changes of hemorheology and atherosclerosis were compared between the two groups. Results: The total effective rate of the treatment group was 95.0%, which was better than 87.5% of the control group (P <0.05). After the first and second week of treatment, the neurological deficit scores of the treatment group were lower than those of the control group (P <0.05) After 3 months, the Fbg, hematocrit, erythrocyte aggregation index, whole blood high shear viscosity and whole blood low shear viscosity of the treatment group were lower than those of the control group (P <0.05). The thickness of the plaque, Pathway and IMT were lower than the control group (P <0.05). Conclusion: Ginkgo biloba injection for the treatment of elderly patients with acute cerebral infarction has a good clinical efficacy, can improve the degree of atherosclerosis and hemorheology indicators.
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