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中药柴胡桂枝汤是由柴胡、桂皮、芍药、姜、甘草、人参、黄芩、半夏和大枣制成的合剂。它对于不同类型的癫痫和其他一些需要镇静的神经病的治疗方面已显示了一定效果。多数的抗癫痫药,例如苯妥英钠,巴比妥仅有对症的抗惊厥作用,且有一定的副作用。柴胡桂枝汤没有副作用,而且对某些病例有较高的疗效。对癫痫和一些兴奋症状,有时它的镇静效果是显著的,但其作用机制尚不清楚。本文从实验神经药理学观点考察了柴胡桂枝汤及其组成药物的镇静作用机制,获得了对
Chinese medicine Chaihu Guizhi soup is a mixture made from Bupleurum, cinnamon, peony, ginger, licorice, ginseng, astragalus, pinellia and jujube. It has shown some effect on the treatment of different types of epilepsy and other neurological diseases requiring sedation. Most antiepileptic drugs, such as sodium phenytoin, and barbital have only symptomatic anticonvulsant effects and have certain side effects. Chaihu Guizhi soup has no side effects, and it has high efficacy in some cases. With regard to epilepsy and some stimulatory symptoms, sometimes its sedative effect is significant, but its mechanism of action is still unclear. This article examined the sedative mechanism of Chaihu Guizhi Decoction and its constituent drugs from the perspective of experimental neuropharmacology and obtained