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摄入过量碘而引起的甲状腺功能亢进症(简称碘甲亢)较少见,易被忽略,现将我们收治的3例报告如下: 例1 男,50岁。因反复心慌、气促10余年,确诊为充血性心肌病,合并室性心动过速,于1985年9月底开始先后两段时间服用乙胺碘呋酮共135天,总量36.3克。近10多天来感怕热、手颤、心烦易怒、失眠、乏力、体重减轻1公斤。既往及家族无甲亢病史。体检:眼征阴性,甲状腺Ⅰ°大,质较硬,无血管杂音,双手细震颤,手心温暖多汗。实验室检查:总三碘甲状腺原氨酸(T_3)143毫微克/分升,总甲状腺素(T_4)25微克/分升,血清促甲状腺激素(TSH)6.4微单位/毫升,甲状腺微粒体抗体及球蛋白抗体均阴性、甲状腺吸碘率24小时为0.8%。1986年2月25日开始乙胺碘呋酮由原来每天0.6克减为0.3克,3月8日停
Over-consumption of iodine caused by hyperthyroidism (referred to as iodine hyperthyroidism) is rare, easily overlooked, now we report the treatment of 3 cases are as follows: Example 1 Male, 50 years old. Due to repeated palpitation, shortness of breath more than 10 years, diagnosed with congestive cardiomyopathy, with ventricular tachycardia, at the end of September 1985 has been taking two periods of amiodarone a total of 135 days, a total of 36.3 grams. Nearly 10 days to feel afraid of heat, trembling hands, upset irritability, insomnia, fatigue, weight loss 1 kg. Past and family history of non-hyperthyroidism. Physical examination: Eye sign negative, thyroid Ⅰ ° large, hard quality, no vascular noise, fine hands tremor, palms warm sweating. Laboratory tests: total triiodothyronine (T_3) at 143 ng / dL, total thyroxine (T_4) at 25 microg / dL, serum thyrotropin (TSH) at 6.4 μM / ml, thyroid microsomal antibody And globulin antibodies were negative, thyroid iodine absorption rate of 24 hours was 0.8%. Beginning on February 25, 1986, amiodarone reduced from 0.6 grams per day to 0.3 grams per day and stopped on March 8