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目的评价化放疗、放疗和化疗治疗肺癌脑转移的疗效。方法化疗加放疗32例,放疗19例,化疗11例。结果化放疗组、放疗组和化疗组的中位生存期分别为6.9月、5.8月、3.6月;1年生存率分别为28.1%、21.1%、0%。化放疗组的疗效虽稍优于放疗组,但在统计学上差异无显著性(P>0.05)。而化放疗组及放疗组明显好于化疗组(P<0.05)。结论化放疗及放疗特别是化放疗是治疗肺癌脑转移的有效治疗方案。
Objective To evaluate the effect of chemotherapy, radiotherapy and chemotherapy on brain metastases of lung cancer. Methods Chemotherapy plus radiotherapy in 32 cases, 19 cases of radiotherapy, chemotherapy in 11 cases. Results The median survival of the chemoradiation group, the radiotherapy group and the chemotherapy group were 6.9 months, 5.8 months and 3.6 months respectively. The 1-year survival rates were 28.1%, 21.1% and 0%, respectively . The efficacy of chemoradiotherapy group was slightly better than that of radiotherapy group, but there was no statistical difference (P> 0.05). The chemoradiotherapy group and radiotherapy group was significantly better than the chemotherapy group (P <0.05). Conclusion Chemoradiotherapy and radiotherapy, especially chemoradiotherapy, is an effective treatment for brain metastases of lung cancer.