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目的:探讨老年高血压患者血同型半胱氨酸(Hcy)与臂踝脉搏波传导速度(baPWV)的关系。方法:将95例老年原发性高血压病患者,按照血Hcy水平的不同,分为2组:低Hcy组52例(血Hcy<11.0μmol/L,男39例,女13例),高Hcy组43例(血Hcy≥11.0μmmol/L,男37例,女6例),另选37例(男29例,女8例)非老年高血压患者为对照组,分别测定并比较3组患者的Hcy、baPWV。结果:老年高血压患者中不同Hcy水平的两组比较,随着血Hcy水平增高,患者的baPWV逐渐升高,两组差异具有统计学意义,低Hcy组﹤高Hcy组(P<0.01)。结论:在老年高血压患者中,baPWV变化和血Hcy水平的关系密切,呈线性正相关。
Objective: To investigate the relationship between plasma homocysteine (Hcy) and brachial-ankle pulse wave velocity (baPWV) in elderly hypertensive patients. Methods: Ninety-five elderly patients with essential hypertension were divided into two groups according to the blood Hcy levels: 52 patients with low Hcy (blood Hcy <11.0μmol / L, 39 males and 13 females), high Hcy group 43 cases (blood Hcy≥11.0μmmol / L, 37 males and 6 females), and another 37 cases (29 males and 8 females) non-elderly hypertensive patients as the control group were measured and compared three groups Patient’s Hcy, baPWV. Results: Compared with the Hcy group, the baPWV increased gradually with the increase of blood Hcy level in two groups with different levels of Hcy in elderly hypertensive patients. There was significant difference between the two groups (P <0.01). Conclusion: In elderly hypertensive patients, the changes of baPWV and blood Hcy levels are closely related to a linear positive correlation.