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文章从中药单体和复方制剂两方面对中药干预肿瘤乏氧微环境的研究进展作一整理,并总结了传统中医药与现代药理机制之间的关联。中药干预肿瘤乏氧微环境的研究进行了很多,但其过程复杂,需要寻找更加特异的靶点,特异性地干预肿瘤乏氧微环境。随着对肿瘤乏氧微环境研究方法的不断改进和理论的完善,中药干预肿瘤乏氧微环境的研究必将受到越来越多的关注,对于实现中药现代化起到重要意义。
This article summarizes the research progress of traditional Chinese medicine (TCM) intervention on tumor hypoxia and microenvironment both from single Chinese medicine and compound preparation and summarizes the correlation between traditional Chinese medicine and modern pharmacological mechanism. However, its process is complex, and it is necessary to find more specific targets to specifically interfere with the tumor hypoxia microenvironment. With the continuous improvement of the research methods of tumor hypoxia and microenvironment and the improvement of the theory, the research on Chinese medicine intervention in the tumor hypoxia and microenvironment will surely receive more and more attention and play an important role in the modernization of traditional Chinese medicine.