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目的:比较5-氨基酮戊酸光动力疗法(ALA-PDT)联合CO2激光与单纯用CO2激光治疗尖锐湿疣的治愈时间,寻找一种能缩短治疗尖锐湿疣治愈时间的方法。方法:将104例尖锐湿疣患者随机分成两组,治疗组52例,用ALA-PDT联合CO2激光治疗;对照组52例,用CO2激光治疗。二组均每周复查1次,若有新发皮损者,重复治疗。结果:治疗组治愈时间与对照组比较差异有统计学意义(χ2=28.82,P<0.01)。结论:ALA-PDT联合CO2激光治疗尖锐湿疣,可明显缩短尖锐湿疣治愈的时间,且不良反应轻微。
OBJECTIVE: To compare the cure time of ALA-PDT with CO2 laser and CO2 laser in the treatment of condyloma acuminatum and to find a way to shorten the cure time of condyloma acuminatum. Methods: A total of 104 patients with condyloma acuminatum were randomly divided into two groups. The treatment group (52 cases) was treated with ALA-PDT combined with CO2 laser. The control group (52 cases) was treated with CO2 laser. The two groups were reviewed once a week, if the new skin lesions were repeated treatment. Results: There was significant difference between the treatment group and the control group (χ2 = 28.82, P <0.01). Conclusion: ALA-PDT combined with CO2 laser treatment of condyloma acuminata, can significantly reduce the cure time of genital warts, and minor adverse reactions.