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目的:了解我院食管癌患者围手术期预防性应用抗菌药的情况。方法:抽取2011年7月～2012年7月出院的食管癌手术病历192份,调查围手术期预防性应用抗菌药的情况。结果:192例食管癌手术患者抗菌药预防使用率为100%,用药品种共10种,单一用药占56.8%,联合用药占43.2%,有128例在术前0.5～2 h预防性给药,平均使用抗菌药时间为(6.9±1.7)d。结论:食管癌患者围手术期预防性应用抗菌药比较合理,但在给药时机、用药疗程及联合用药方面有待改进。
Objective: To understand the perioperative prophylactic use of antibacterials in patients with esophageal cancer in our hospital. Methods: 192 cases of esophageal cancer surgical records discharged from July 2011 to July 2012 were collected, and the prophylactic use of antibacterials during the perioperative period was investigated. Results: The prevention and cure rate of antibacterials in 192 cases of esophageal cancer patients was 100%. There were 10 kinds of drugs, 56.8% of the single drug, 43.2% of the combined drugs, 128 of them were prophylactically administered 0.5-2 h before operation, The average duration of antibacterial use was (6.9 ± 1.7) days. Conclusion: The prophylactic use of antimicrobial agents in patients with esophageal cancer is reasonable, but the timing of drug delivery, drug treatment and combination therapy need to be improved.