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目的:了解我院住院患儿抗菌药的应用情况,促进临床合理使用抗菌药。方法:采用回顾性调查方法,对2012年1～3月出院的儿科住院患者使用抗菌物的品种、用药频度、联合用药等进行调查分析。结果:1 188例出院患儿中有1 099例应用抗菌药,使用率达92.5%,使用强度为每百人天66.6DDDs(按成人规定日剂量标准计算),涉及5大类19种,其中单用1 040例(94.6%),二联59例(5.4%),无三联及以上用药,药物敏感度试验及病原学送检率为76.3%。结论:抗菌药使用率过高,使用强度偏大,应采取有效措施,加强抗菌药使用管理。
Objective: To understand the application of antibacterials in hospitalized children in our hospital and to promote the rational use of antibacterials in clinic. Methods: A retrospective survey was conducted to investigate the use of antimicrobial species, frequency of drug use and combination therapy in pediatric inpatients discharged from January to March in 2012. Results: Among the 1 188 cases of discharged children, 1 099 cases were used antibacterial drugs, the usage rate reached 92.5%, and the intensity of use was 66.6DDDs per 100 person days (calculated according to the adult daily dose standard) There were 1 040 cases (94.6%) and 59 cases (5.4%) in two groups without medication of triple combination or above. The drug susceptibility test and etiological examination rate were 76.3%. Conclusion: The antibacterial drug usage rate is too high, the use of strength is too large, effective measures should be taken to strengthen the use of antimicrobial drug management.