论文部分内容阅读
先天愚型(Down综合征)是精神发育不全病,也是一种大脑发育不全症的常见疾病。先天愚型是常染色体畸变引起的遗传病,最常见的核型是21三体。患者主要表现为痴呆。先天愚型与环境因素有关,因此研究本病对优生学和促进环境保护都有一定意义。目前国内外有大量报道,研究巳深入到分子水平。据报道,1973年后已确定过氧化物歧化酶-I(SOD-I)的基因位于第21号常染色体长臂2区第2带第1小带(21q22.1),这种基因与先天愚型临床发病有关。21三体型先天愚型临床上有典型症状;易位型则没有典型临床症状;而嵌合型常有
Down syndrome syndrome is a psychosis and is also a common disease of the brain hypoplasia. Down’s syndrome is a genetic disease caused by autosomal aberrations, the most common karyotype is trisomy 21. Patients mainly manifested as dementia. Down’s syndrome and environmental factors, so the study of eugenics and promote environmental protection are of some significance. At present, there are a lot of reports at home and abroad, and research has gone deep into the molecular level. It has been reported that the gene for superoxide dismutase-I (SOD-I) has been identified since 1973 as being located in the first zygosity zone 2 (21q22.1) of region 2 of the long arm of autosome No.21, Stupid clinical onset. 21 trisomy type clinical manifestations of typical symptoms; translocation type is no typical clinical symptoms; and chimeric often