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目的:研究不同措施预防人工流产术后宫腔粘连的临床效果。方法:对800例因早孕进行人工流产手术的多次流产患者随机分组,几丁糖子宫腔内应用组(试验组A)、超导可视人工流产组(试验组B)、人工流产术后补佳乐+黄体酮人工周期组(试验组C),及无干预措施组(对照组D),所有患者术后随访6个月以上,对一般情况、手术情况、手术并发症、术后月经量变化、宫腔粘连情况进行总结分析。结果:3个试验组与对照组相比,一般情况、手术中情况(手术时间、术后绒毛大小)无差异,具有可比性。术后月经量改变情况、发生宫腔粘连情况,试验组A、C均少于对照组D,差异有显著统计学意义,(χ2A=14.36,PA=0.008;χ2C=15.61,PC=0.002);试验组B少于对照组D,有一般差异性,(χ2B=12.09,PB=0.015)。结论:3种干预方案均可减少人工流产术后宫腔粘连的发生率,尤其试验组A、C与无干预方案组比较,差异有显著统计学意义,3种方案可针对不同人群使用,操作简便、疗效满意,有临床推广意义。
Objective: To study the clinical effect of different measures to prevent intrauterine adhesions after induced abortion. Methods: A total of 800 patients with multiple abortion due to early pregnancy were randomized into two groups: chitosan intrauterine application group (experimental group A), superconducting visible artificial abortion group (experimental group B), artificial abortion (N = 10). The patients in control group were given buprenorphine + progesterone artificial phase group (experimental group C) and no intervention group (control group D). All the patients were followed up for more than 6 months. The general conditions, operation conditions, complications, Volume changes, intrauterine adhesions were analyzed. Results: Compared with the control group, there was no difference between the three experimental groups and the control group in general conditions, operation conditions (operation time, postoperative villus size) and comparability. There were significant differences between the two groups (χ2A = 14.36, PA = 0.008; χ2C = 15.61, PC = 0.002); There was a general difference between experimental group B and control group D (χ2B = 12.09, PB = 0.015). Conclusion: All three interventions can reduce the incidence of intrauterine adhesions after induced abortion, especially in experimental group A, C compared with non-intervention group, the difference was statistically significant, three kinds of programs can be used for different populations, the operation Simple, effective, with clinical significance.