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目的:观察芪丹通脉片(QDTMT)治疗冠心病心绞痛的临床疗效。方法:将205例心绞痛患者,随机分为芪丹通脉片组和养心氏组;分别口服芪丹通脉片4片,养心氏片2片,观察患者心绞痛发作次数、疼痛程度、持续时间、硝酸甘油服用量,以及胸闷、心悸、气短、倦怠乏力、自汗等中医症候和心电图的变化。结果:芪丹通脉片组患者心绞痛总有效率为78.6%、显效率35.9%,养心氏组总有效率为71.5%、显效率30.3%,芪丹通脉片组中医证候显效率35.9%、总有效率为91.3%,养心氏组显效率27.5%,总有效率为86.4%,芪丹通脉片组心电图总有效率45.6%、显效率21.4%,养心氏组总有效率34.3%、显效率9.8%;两组心绞痛和中医证候总有效率相比无统计学差异,而芪丹通脉片组心电图总有效率显著高于养心氏组(P<0.05)。结论:芪丹通脉片对心绞痛有较好的临床疗效。
Objective: To observe the curative effect of QDTMT on angina pectoris of coronary heart disease. Methods: 205 patients with angina pectoris were randomly divided into QDTT group and YangXinTai group. Four tablets of QDTD and two tablets of YangXing tablets were orally administered respectively. The number of angina pectoris and the degree of pain were observed Time, consumption of nitroglycerin, and chest tightness, palpitations, shortness of breath, fatigue, spontaneous perspiration and other TCM symptoms and ECG changes. Results: The total effective rate of angina pectoris in QDTT group was 78.6%, the effective rate was 35.9%, the total effective rate in Yangshent’s group was 71.5% and the effective rate was 30.3%. The effective rate of TCM syndrome in QDTT group was 35.9% %, The total effective rate was 91.3%, Yangxian’s effective rate was 27.5%, the total effective rate was 86.4%, Qidan Tongmai group electrocardiogram total effective rate 45.6%, effective rate 21.4%, Yang Xin’s total effective rate 34.3% and markedly effective rate 9.8% respectively. There was no significant difference between the two groups in the total effective rate of angina pectoris and traditional Chinese medicine syndrome, while the total effective rate of QDTT group was significantly higher than that of Yangxin group (P <0.05). Conclusion: Qidan Tongmai tablet has good clinical effect on angina pectoris.