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近十年来,恶性疟对氯喹的抗性已成为东南亚许多地区的重要问题。Ramkaran等(1969)观察到感染抗氯喹株伯氏疟原虫的小鼠,在用氯喹治疗后增强了斯氏按蚊的感染力,这是抗性株很快发生的一种解释。本文作者为了探明抗氯喹株恶性疟用氯喹治疗后
Over the past decade, the resistance of chloroquine to falciparum malaria has become an important issue in many parts of Southeast Asia. Ramkaran et al. (1969) observed that mice infected with chloroquine-resistant Plasmodium berghei increased the infectivity of An. mosquito after treatment with chloroquine, an explanation for the rapid emergence of resistant strains. The authors of this study sought to identify chloroquine resistant chloroquine resistant strains of Plasmodium falciparum