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探讨克罗米芬 (CC) /人绝经期促性腺激素 (HMG)单次用药联合方案 (简称小剂量刺激法 )在多囊卵巢综合征患者中的疗效。对 38例共 45个周期采用 CC5 0 mg/ d×5 d后单次给予 HMG1 5 0 IU的联合方案的卵泡发育情况、排卵及妊娠情况进行了监测 ,并与 CC 32例 43个周期相比较。结果小剂量组妊娠率 34% (1 3/ 38) ,周期排卵率 84%(38/ 45 ) ,卵巢过度刺激综合征 (OHSS)发生 1例 ;CC组妊娠率 1 2 % (3/ 2 4) ,周期排卵率5 6 % (2 4/ 43) ,OHSS1例。结果表明小剂量刺激法是一种安全有效的诱导排卵方案。
To investigate the efficacy of clomiphene citrate (CC) / human menopausal gonadotropin (HMG) single-agent combination regimen (abbreviated as low-dose stimulation) in patients with polycystic ovary syndrome. Follicular development, ovulation and pregnancy in 38 patients with 45 cycles of CC5 0 mg / d × 5 d and single administration of HMG1 50 IU were monitored and compared with those of 32 cycles of CC 32 . Results The pregnancy rate of low dose group was 34% (13/38), the rate of ovulation was 84% (38/45) and the incidence of ovarian hyperstimulation syndrome (OHSS) was 1 case. The pregnancy rate of CC group was 12% (3/24 ), Ovulation rate 56% (24/43), OHSS1 cases. The results show that low-dose stimulation is a safe and effective ovulation induction program.