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OBJECTIVE:To compare the conventional treatment and CVVH in the severe acute pancreatitis for the prevention of pseudocyst and abscess. PATIENTS AND METHODS: Forty two patients were divided into two t
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OBJECTIVE:To compare the conventional treatment and CVVH in the severe acute pancreatitis for the prevention of pseudocyst and abscess. PATIENTS AND METHODS: Forty two patients were divided into two treatment groups: Conventional treatment group contain 24 patients and CVVH 18. Conventional treatment group patients were treated symptomatically and according to the causes. CVVH group patients were treated symptomatically and CVVH was done within 2 hours of admission. RESULTS:In both the groups there was decrease in amylase, Lipase, CRP, IL-6, IL-10, TNF-alpha, RANSON SCORE, Balthazar score and APACHE-II SCORE after 72 hours, but decrease was more in CVVH patients. There were no any local pancreatic complications in CVVH patients but 1 patient had an acute peripancreatic fluid collection (APFC), 2 patients had Pseudocyst, and 2 patients had walled-off necrosis (WON) and mortality one was seen in conventional treatment group. Conclusions:Our study shows that early CVVH can prevent the formation pseudocyst and abscess in SAP patients.
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