SUMO-specific protease 2 is critical for the regulation of M-current through PLCb4 and Kv7 pathway d

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户：sallen009

【摘要】

：

Sudden unexplained death in epilepsy(SUDEP)is the most common and primary cause of premature mortality in epilepsy.Hyper-SUMOylation of the Kv7 potassium channel diminish the M-current and causes SUDE

【作者】

：

Xu Chen Shanshan Zhang Jifang Huang Wangying Dong Yuhong Zhang Xiaojun Long Biying Zhao Siming An Jinke Cheng Hongmei Wu Yitao Qi

【机构】

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College of life science,Shaanxi Normal University,Shaanxi Xi'an,710119,China

【出处】

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中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议

【发表日期】

：

2018年10期

【关键词】

：

SUMOylation Sentrin/SUMO-specific protease 2 SUDEP potassium channels Retigabine

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SUMO-specific protease 2 is critical for the regulation of M-current through PLCb4 and Kv7 pathway d

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