Ortho-C(sp2)-H Functionalizations of Benzaldehydes using TDG

来源 :中国化学会第十三届全国有机合成化学学术研讨会 | 被引量 : 0次 | 上传用户：zhuobin0904

【摘要】

：

　　More recently,Yu group disclosed the first Pd-catalyzed C(sp3)-H functionalization of aldehydes and ketones using transient directing group(TDG) strategy.He

【作者】

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Hu Yan Liu Xi-Hai Zhang Fang-Lin

【机构】

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DepartmentSchoolofChemistry,ChemicalEngineeringandLifeSciences,WuhanUniversityofTechnology,Wuhan4300

【出处】

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中国化学会第十三届全国有机合成化学学术研讨会

【发表日期】

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2016年10期

【关键词】

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transient directing group benzaldehydes C-H functionalization site-selective

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　　More recently,Yu group disclosed the first Pd-catalyzed C(sp3)-H functionalization of aldehydes and ketones using transient directing group(TDG) strategy.Herein,we report a diverse series of ortho-C(sp2)-H functionalization reactions of benzaldehydes using transient directing group strategy.This approach allows a site-selective formation of C(sp2)-Cl,C(sp2)-Br bonds in the presence of stronger directing groups such as amides,carbamates,and heterocycles.Scheme1.Catalytic,Selective Directed C-H Functionalization with Multiple Coordinating Groups.

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Ortho-C(sp2)-H Functionalizations of Benzaldehydes using TDG

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