【摘 要】
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Over the past decades,N-heterocyclic carbenes (NHCs) have developed into a powerful kind catalysts for organic syntheses.Thus numerous efforts have been to
【机 构】
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SchoolofChemistryandChemicalEngineering,JiangsuKeyLaboratoryofGreenSyntheticChemistryforFunctionalMa
【出 处】
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中国化学会第十三届全国有机合成化学学术研讨会
论文部分内容阅读
Over the past decades,N-heterocyclic carbenes (NHCs) have developed into a powerful kind catalysts for organic syntheses.Thus numerous efforts have been to the generation and reactivity of NHC-bounded intermediates including enolates,homoenolates and vinyl enolates.Herein,we would like to present our recent work on the generation of these key intermediates from easily accessible precursors such as α-bromoenal,α,β-unsaturated carboxylic acids and their derivatives.Subsequently,the formal[3+2],[3+3]or[4+2]cycloaddition of these intermediates with reactive species could provide new alternatives to five-membered or six-membered heterocycles.
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