【摘 要】
：
MicroRNAs (miRNAs) are a class of small non-coding RNAs that degrade or block target mRNAs at the posttranscriptional level.Many studies have shown that miRNA dysregulation is involved in cancer initi
【机 构】
：
Department of Biochemistry and Molecular Biology, Fourth Military Medical University China
论文部分内容阅读
MicroRNAs (miRNAs) are a class of small non-coding RNAs that degrade or block target mRNAs at the posttranscriptional level.Many studies have shown that miRNA dysregulation is involved in cancer initiation, invasion, metastasis, and so forth.Notably, recent studies have revealed secretory miRNA levels in blood and other body fluids to correlate significantly with cancer progression,therapeutic response and patient survival.Thus, secretory miRNAs have demonstrated great potential as powerful and non-invasive cancer biomarkers.
其他文献
Liver cancer is the third most common cancer globally and most patients die within a year of the disease.Evidence suggests that circulating tumor cells (CTCs) are responsible for the hematogenous spre
MiR-378 was reported down-regulated expression in several cancers including hepatocellular carcinoma(HCC).We have previously shown that serum miR-378 was significantly lower in patients of HBV related
Solanum cathayanum, one of Solanum genus plants belonging to the Solanum family, is particular to China, which is distributed in tropical and subtropical regions.It has long been used as a folk medici
Merkel cell carcinoma (MCC) of the skin is a rare, aggressive cutaneous malignancy that predominantly affects elderly Caucasians with a propensity for local recurrences and regional lymph node metasta
Capecitabine and Oxalipaltin (CAPOX) are usually used as first-line therapy in most of the gastrointestinal (GI) advanced tumors, with or without associations with biological agents, such as Bevacizum
Breast cancer is the most common malignancy in Singaporean women.More patients undergo mastectomy compared to breast conservative surgery.However, the proportion of patients who underwent breast recon
In the late 90s, the massive availability of X-ray digital detectors supported a great development of Computer Aided Diagnosis (CADx) systems for helping radiologists in making more accurate diagnosis
Chromosomal instability is the most common genetic abnormality in sporadic colorectal cancer (CRC).By loss of heterozygosity approach, we identified Protocadherin 10 (PCDH 10) gene at chromosome 4q28
Cancer is the leading cause of death in human, while more than 90% of cancer patients die from cancer metastasis.Currently there is no effective treatment for cancer metastasis, this is mainly due to
Study found that excessive amounts of ROS promote apoptosis, and has become one of new cancer therapeutic strategies.Kronopolites svenhedind (Verhoeff) (KSV) has shown potent anticancer activities on