Use of ZFNs for targeted mutagenesis in mice

来源 :The 11th transgenic Technology Meeting ISTT2013 ( 第十一届国际转基因技 | 被引量 : 0次 | 上传用户:qq68813172
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Fox Chase Cancer Center, Philadelphia, USA Characterization of transcriptional cis-acting elements is important for understanding the regulation of individual genes and the biological processesthat they control.This task is commonly carried out through transient transfection of cell lines with an artificial reporter construct.
其他文献
十足目内部的系统发育关系存在争议,基于形态学的分析提出了诸多假设.而利用线粒体DNA和核rDNA序列的分子系统发育研究与形态学分析结果产生了冲突.在国际上,我们首次开发了
我国是世界上最早开展水产养殖生物定向选择育种的国家之一,已经选育出一批鱼、虾、贝、藻等各类水产养殖良种并推广应用.近年来,随着分子生物技术特别是基因组学研究的飞速
2013年"蛟龙号"载人深潜器试验性应用航次南海航段的深潜考察分3个阶段进行.第一阶段:冷泉区-于2013年6月17-20日在“蛟龙冷泉”作业区共进行了4次下潜.其中科学家下潜3次.
会议
The first reports of successful cryopreservation of mouse spermatozoa were published in 1990 by three independent groups of Japanese researchers (Okuyama et al.
会议
Phenomics involves the systematic characterisation of phenotypes on a genome-wide scale.It is transdisciplinary, calling upon a range of approaches and experime
会议
本文报告了对虾主要疾病病原白斑综合症病毒(white spot syndrome virus, WSSV)宿主范围、感染途径、传播途径、急性感染与潜伏感染特性、潜伏感染转为急性感染与养殖水体理
  Aluminum(Al)toxicity is a major limitation to crop yields on acid soils worldwide.Many crop species have evolved Al tolerance mechanisms based on root efflu
Natural mammalian haploid only exists in germ cells and occasionally occurs in rare tumor cells harboring genetic mutations.In theory, mammalian haploid stem ce
会议
Primary cicatricial alopecias (PCAs) are a group of permanent hair loss disorders, of which the pathogenesis is still poorly understood.The alopecia and excoria
会议
The Knockout Mouse Production and Phenotyping (KOMP2) project is the next phase of theKOMP project designed to generate mouse lines and conduct broad based and
会议