From Haploid Stem Cells to Transgenic Mice

来源 :The 11th transgenic Technology Meeting ISTT2013 ( 第十一届国际转基因技 | 被引量 : 0次 | 上传用户：snowbar

【摘要】

：

Natural mammalian haploid only exists in germ cells and occasionally occurs in rare tumor cells harboring genetic mutations.In theory, mammalian haploid stem ce

【作者】

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Zhou Q Li TD Li X WangLB ZhengQy ShengC WuHJ LiuZH LiuL Wang L Wang XJ Li W Zhao XY ShuaiL WanHF DongMZ Wang M Sang LS Feng CJ LuoGZ

【机构】

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StateKeyLaboratoryofReproductiveBiology,InstituteofZoology,ChineseAcademyofSciences,Beijing,ChinaSta

【出处】

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The 11th transgenic Technology Meeting ISTT2013 ( 第十一届国际转基因技

【发表日期】

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2013年2期

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Natural mammalian haploid only exists in germ cells and occasionally occurs in rare tumor cells harboring genetic mutations.In theory, mammalian haploid stem cells could be derived from parthenogenesis or androgenetic development, or could be differentiated from diploid stem cells or induced pluripotent stem (iPS) cells.Recently, haploid embryonic stem (ES) cells have been successfully derived from Medaka Fish and mouse embryos.

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From Haploid Stem Cells to Transgenic Mice

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