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In the present presentation,an overview is given on the latest development of Process Analytical Technologies(PAT)analyzers for at-line,on-line and in-line process monitoring and understanding.The goal is to implement PAT technologies in various industries,including pharmaceutical,chemical,food/feed sectors,to meet the more demanding process monitoring for the purpose of improving productivity,ensuring product quality,reducing operational cost.With the implementation of PAT,it becomes possible for automated process monitoring for real-time process control and adjustment to optimize the production processes.