Microwave Accelerated Efficient Traceless Synthetic Strategy for Highly Functionalized Aminoimidazol

来源 :第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 | 被引量 : 0次 | 上传用户：lxy850628

【摘要】

：

【作者】

：

Manikandan Selvaraju Chung-Ming Sun

【机构】

：

Laboratory of Combinatorial Drug Discovery,Department of Applied Chemistry,National Chiao Tung Unive

【出处】

：

第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会

【发表日期】

：

2012年8期

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　　An efficient traceless synthetic strategy for the soluble polymer supported synthesis of trisubstituted aminoimidazolone and disubstituted benzylidene-aminoimidazolone has been developed under microwave conditions.Nucleophilic addition of soluble polymer bound amino acids with isothiocyanates,base promoted intramolecular ring closure followed by arnination and auto-oxidation strategy provided fast synthetic route towards diverse aminoimidazolone library.

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Microwave Accelerated Efficient Traceless Synthetic Strategy for Highly Functionalized Aminoimidazol

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