An Improved Synthesis of Methyl Protodioscin:A Direct E-ring Opening by BF3-Et2O/Ac2O from Dioscin E

来源 :第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 | 被引量 : 0次 | 上传用户：xiegenda

【摘要】

：

A direct E-ring opening of dioscin ester by BF3-Et2O/Ac2O was studied,and methyl protodioscin was synthesized from dioscin ester in three steps with a total yield of 44%.The details of the E-ring open

【作者】

：

Bo Wang Yang Liu Maosheng Cheng

【机构】

：

Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education,School of Pharma

【出处】

：

第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会

【发表日期】

：

2012年8期

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An Improved Synthesis of Methyl Protodioscin:A Direct E-ring Opening by BF3-Et2O/Ac2O from Dioscin E

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