【摘 要】
：
Alpha B-crystallin (CRYAB) is a protein functions as "molecular chaperone" in preservation intracellular architecture, cell membrane and highly antiapoptotic.Abnormal CRYAB expression is a prognostic
【机 构】
：
Terry Fox Cancer Research Lab, China Medical University Hospital;Graduate Institute of Basic Medical
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Alpha B-crystallin (CRYAB) is a protein functions as "molecular chaperone" in preservation intracellular architecture, cell membrane and highly antiapoptotic.Abnormal CRYAB expression is a prognostic biomarker for oral cancer, while its genomic variations and the association with carcinogenesis are never studied.Therefore, we hypothesized that CRYAB single nucleotide polymorphisms may be associated with oral cancer risk.In this hospital-based study, the association of CRYAB A-1215G (rs2228387), C-802G (rsl4133) and intron2 (rs2070894) polymorphisms with oral cancer in a Taiwan was investigated.
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