【摘 要】
：
Bacillus licheniformis (B.licheniformis) is a Gram-positive bacterium that is widely used in agriculture as a probiotic and microbial fertilizer,and in biot
【机 构】
：
华中农业大学信息学院,农业生物信息湖北省重点实验室,武汉,430070
【出 处】
：
第七届全国生物信息学与系统生物学学术大会
论文部分内容阅读
Bacillus licheniformis (B.licheniformis) is a Gram-positive bacterium that is widely used in agriculture as a probiotic and microbial fertilizer,and in biotechnology industry for production of enzymes,antibiotics,and poly-γ-glutamic acid (γ-PGA).We comprehensively study the genome,transcriptome,biological network,and molecular mechanism of high production of γ-PGA under salt stress.The complete genome of B.licheniformis WX-02 comprises a circular chromosome of 4,286,821 base-pairs containing 4,512 protein-coding genes with an average GC content of 46.1%.Based on the transcriptome data,we identified 90 small RNAs,1,169 antisense transcripts and 871 operon structures,and 234 genes were up-regulated and 1,439 genes were down-regulated in salt stress condition.
其他文献
Background: Single-cell RNA sequencing (scRNA-seq) is an emerging technology that enables high resolution detection of heterogeneities between cells.One imp
Background: Over the past decade,owing to rapid advances in the next-generation sequencing (NGS) technology,the cost of DNA sequencing has been reduced by o
Nematodes are considered major pests in agriculture.In recent years,overdose usage of chemical pesticides causes environmental damages and becomes a thread
The Encyclopedia of DNA Elements (ENCODE) Consortium has generated hundreds of high throughput genomic datasets with the goal of cataloging functional eleme
Gene fusions are often driving events in human cancers.The simultaneous availability of whole genome and RNA sequencing data for a large panel of cancer sam
The rapid advancement of next-generation sequencing technology has generated a deluge of genomic data from domesticated dogs and their wild ancestor,grey wo
Gastric cancer (GC) is one of the most common malignancies and the one of the greatest threats to human health,accounting for over 10% of tumour-related mor
Mitochondria are the important organelles that affect tumor initiation,growth,survival,and metastasis.The mitochondrial proteostasis was largely maintained
DNA replication begins at replication origins in all three domains of life.In bacteria,replication typically initiates from a single replication origin (ori
Post-translational modifications (PTMs),such as phosphorylation,acetylation and ubiquitination,play essential roles in the regulation of almost all of biolo