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  5. Molecular mechanism of substrate specificity for heparan sulfate 2-O-sulfotransferase

Molecular mechanism of substrate specificity for heparan sulfate 2-O-sulfotransferase

来源 :2014年全国糖生物学学术会议 | 被引量 : 0次 | 上传用户：bcdagjcly
【摘 要】
：
Heparansulfate (HS) is an abundantpolysaccharide in the animal kingdom withessential physiological functions.HS is composed of sulfated saccharides that arebiosynthesized through a complex pathwayinvo
【作 者】
：
Chunhui Liu Juzheng Sheng Juno M.Krahn Lalith Perera Yongmei Xn Pohung Hsieh Wenfang Dou Jian Liu Lars C.Pedersen 
【机 构】
：
Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of Nor
【出 处】
：
2014年全国糖生物学学术会议
【发表日期】
：
2014年8期
【关键词】
：
Heparan sulfate 2-O-sulfatransferase substrate specificity crystal structure sit 
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Heparansulfate (HS) is an abundantpolysaccharide in the animal kingdom withessential physiological functions.HS is composed of sulfated saccharides that arebiosynthesized through a complex pathwayinvolving multiple enzymes.In vivoregulation of this process remains unclear.
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