Notch signaling modulates proliferative vitreoretinopathy via regulating retinal pigment epithelial-

来源 :第八届中国眼科学和视觉科学研究大会 | 被引量 : 0次 | 上传用户：bear1634

【摘要】

：

【作者】

：

zhang jingjing yuan gongqiang dong muchen liu ting meng lili zhang ting zhou qingjun shi weiyun

【机构】

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Shandong Eye Hospital Shandong Eye Institute

【出处】

：

第八届中国眼科学和视觉科学研究大会

【发表日期】

：

2016年5期

【关键词】

：

Notch signaling endothelial-to-mesenchymal transition retinal pigment epithelial

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　　Purpose To observe the involvement of Notch signaling in the epithelial-mesenchymal transition(EMT)of retinal pigment epithelial(RPE)cells and the pathogenesis of proliferative vitreoretinopathy(PVR).Methods In vitro cultivated human RPE cells(ARPE-19)were treated with 10 ng/ml transforming growth factor(TGF)-β1 for 24,48,and 72 h.

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Notch signaling modulates proliferative vitreoretinopathy via regulating retinal pigment epithelial-

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