【摘 要】
：
Starting from commercially available natural rosin derivatives,a class of bifunctional rosin-derived amine thiourea catalysts were designed and synthesized.In my research work,encouraged by these eleg
【机 构】
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Key Laboratory of Preclinical Study for New Drugs of Gansu Province,School of Basic Medical Sciences
【出 处】
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第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会
论文部分内容阅读
Starting from commercially available natural rosin derivatives,a class of bifunctional rosin-derived amine thiourea catalysts were designed and synthesized.In my research work,encouraged by these elegant advances and the establishment of novel efficient catalytic system,a variety of new optically active non-natural amino acids had been synthesized by using asymmetric synthesis strategy.Especially the use of the doubly stereocontrolled asymmetric synthesis approach could facilitate to achieve the efficient synthesis of a variety of new optically active non-natural amino acids with different configurations(non-natural α-or β-prolines,non-natural α-amino acids,non-natural β-amino acids,non-natural γ-amino acids,non-natural β-hydroxy-α-amino acids,hydroxy-substituted non-natural β-amino acids,and other no-natural chiral amino acids),including several types of non-natural amino acids are the first synthesis.
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