Introduction:For cardiovascular tissue-engineered application, blood compatibility plays a critical role for intravascular grafts to maintain patency.It has been reported that the rapid growth of endo
Objects:Urine-derived stem cells (USCs) have the ability to differentiate into the osteogenic lineage.Previous studies have raised the possibility that USCs could be used for hone repair.
Objective:Human induced pluripotent stem cell-derived mesenchymal stem cells (hiPSC-MSCs) have emerged as a promising alternative for stem cell transplantation therapy.
Objective:Synthetic hydroxyapatite nanoparticles (HANPs) are widely used in nanomedicine fields.The delivery of nanomedicine to the bloodstream exposes the cardiovascular system to a potential threat.
Objects:Boron is an important trace element in bone development and regeneration.Bioactive borate glass has been widely used in the treatment of osteomyelitis due to its excellent bioactivity and drug
Object:It has been reported that human urine-derived stem cells (USCs) have great application potential for cytotherapy as they can be easily obtained using non-invasive and simple procedures and they
目的:人工神经导管应用于周围神经损伤修复已经成为当前生物材料与组织工程学科主要研究方向之一。当前已研究的人工神经导管多是中空的管道,这就使得其在神经修复时难以给雪旺细胞的生长提供支持,从而不利于长距离神经导管的修复。因此,本实验基于相分离法通过模具制备出具有多通道的内层导管结构,并结合静电纺丝提高其力学性能,制备出双层多通道的神经导管支架。
目的:本研究通过温和还原法制备聚谷氨酸(PGA)稳定的Fe3O4纳米颗粒,以期获得具有良好水溶性、胶体稳定性、高T2弛豫率、良好生物相容性、良好体内造影效果的超顺磁性氧化铁(SPIO)纳米颗粒,用于磁共振成像(MRI)造影剂。
引言:传统的金属骨骼内植物具有以下缺点:(1)体内电解腐蚀;(2)较高的印度和较低的弹性;(3)质量大,不利于日常活动与锻炼;(4)对核磁共振有干扰;(5)需要进一步的手术移除内植物,增加了病人的疼痛与负担。本课题旨在探讨可吸收超高分子量聚-DL-乳酸(PolyD,L-lactic acid,PDLLA)接骨板作为缓释重组人骨形态发生蛋白-2(rhBMP-2)的载体的优越性,通过体内活性实验来评估
目的:介孔硅纳米粒子(Mesoporous silica nanoparticles,MSN)拥有诸多优良性能,如粒径和孔径可调,易于表面修饰,生物相容性良好等,这使得其作为药物载体在生物医学领域得到了较为广泛和深入的研究。为提高MSN药物释放系统的靶向性,并使其在肿瘤部位异于正常部位的微环境下进行响应性释放,在MSN表面修饰智能型"门禁"和靶向分子是MSN药物载体的研究热点。