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目的：本研究通过温和还原法制备聚谷氨酸(PGA)稳定的Fe3O4纳米颗粒，以期获得具有良好水溶性、胶体稳定性、高T2弛豫率、良好生物相容性、良好体内造影效果的超顺磁性氧化铁(SPIO)纳米颗粒，用于磁共振成像(MRI)造影剂。
聚谷氨酸稳定的磁性氧化铁纳米颗粒的制备及其生物医学应用
【摘 要】
：
目的：本研究通过温和还原法制备聚谷氨酸(PGA)稳定的Fe3O4纳米颗粒，以期获得具有良好水溶性、胶体稳定性、高T2弛豫率、良好生物相容性、良好体内造影效果的超顺磁性氧化铁(SPIO)纳米颗粒，用于磁共振成像(MRI)造影剂。
【机 构】
：
东华大学材料科学与工程学院,上海201620 东华大学化学化工与生物工程学院,上海201620
【出 处】
：
2014年第十四届上海地区医用生物材料研讨会
【发表日期】
：
2015年8期
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