Biobank and its Application in Translational Medicine

来源 :2013第六届世界癌症大会 | 被引量 : 0次 | 上传用户:zxcasd456
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Biobank is a type of biorepository that stores biological samples for use in research.It plays a major role in prognosis, diagnosis and treatment of human diseases.The development of translational medicine calls for a large quantity of human samples of high quality.Over the past 9 years, we has established a set of standard operation procedures (SOP) for bio-sample collection, transportation,storage, quality control system and safety monitoring system and developed information management software.
其他文献
To identify potential microRNA (miRNA) links between Smad3, a mediator of TGF-β (transforming growth factor-β) signaling, and E-cadherin, we characterized the miRNA profiles of two gastric cancer cell
会议
The transcription factor E2F, the main target of the tumor suppressor RB, plays central roles in activation of growth-promoting genes through physiological inactivation of RB by growth stimulation.E2F
会议
CD44 is a cell-surface glycoprotein, which participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis.However,
会议
Carbonic anhydrase (CA) inhibitors have been proposed as a new class of antitumor agents.The expression of CA Ⅸ, VEGF and the activity of caspase-3 were evaluated in human renal cell carcinoma biopsie
会议
Liver cancer or hepatocellular carcinoma is one of the leading causes of cancer-related deaths.Conventional chemotherapies are limited by the development of drug resistance and various side effects.Be
会议
Patients with neuroblastoma due to N-Myc oncogene-amplification die of tumour metastasis.However, little is known about how N-Myc induces cell migration, invasion and metastasis.The histone demethylas
会议
MicroRNAs (miRNAs) regulate tumor progression and invasion via direct interaction with target messenger RNAs (mRNAs).We defined miRNAs involved in cancer metastasis (metastamirs) using an established
会议
The transcription factor signal transducer and activator of transcription 3 (STAT3) contributes to cell proliferation, apoptosis, and motility in human cancer cells.We aim to elucidate the function of
会议
The non-classical HLA class I antigen HLA-G has been suggested to be part of strategies for tumor cells to avoid from host immunosurveillance.Aberrant HLA-G expression was frequently detected in metas
会议
Human papillomavirus (HPV) is associated with different malignancies but its role in the pathogenesis of ovarian cancer is controversial.This study investigated the possible role of human papillomavir
会议