【摘 要】
：
Sustaining blood retention for theranostic nanoparticles is a big challenge.Various approaches have been attempted and have demonstrated some success,but limitations remain.In theory,peptides capable
【机 构】
：
School of Medicine,South China University of Technology,Guangzhou,China
【出 处】
：
第三届国际纳米药物大会 ChinaNanomedicine 2018 The 3rd International Con
论文部分内容阅读
Sustaining blood retention for theranostic nanoparticles is a big challenge.Various approaches have been attempted and have demonstrated some success,but limitations remain.In theory,peptides capable of increasing blood residence time for M13 bacteriophage,a rod-shaped nanoparticle self-assembled from proteins and nucleic acids,should also prolong blood circulation for engineered nanoparticles.
其他文献
Herein,a photothermal stimulation strategy for mitochondria-specific heat shock and drug release is developed to maximize the synergistic antitumor effects with minimal side effects.
In view of compromised effects of nano drug delivery systems(DDSs)on cancer due to multi-drug resistance(MDR)and premature drug release,and the increasing interest of Au nanoparticles in biomedicine,w
The nano-vehicles were developed based on natural polysaccharidechitosan with different modification.Hydrophobic or hydrophilic segment with tumor microenvironmental sensitivities was grafted to chito
Conventional polymer-drug conjugates have been translated into the clinic; however,they intrinsically lack near infrared(NIR)absorbing attribute,hindering them from cancer photothermal therapy and mul
Proteins play an important role in biomedicine,ranging from basic biomedical research to diagnosis and therapy of diseases.Many of these applications depend on the ability to add new functions through
It is of high demand to develop imaging-guided smart nanoplatforms for combinational photodynamic/chemo-therapy of tumor.As depicted in Figure 1,low molecular weight heparin(LWMH)was used as the backb
Atherosclerosis,a chronic inflammatory condition,is the most manifest contributor to myocardial infarction,ischemic stroke,and atherosclerotic aneurysm.Therapeutic approaches are generally employed to
By mimicking high density lipoprotein in the central nervous system(CNS),we constructed discoidal apolipoprotein E3-reconstituted high-density lipoprotein(ApoE3-rHDL)as an efficient nanoplatform that
Functional inorganic nanoparticles have shown great potentials in diagnosing major diseases such as cancer,atherosclerosis,etc.Through past years,we have been developing versatile functional nanoparti
A water-soluble photosensitizer that demonstrates superior photodynamic therapy(PDT)efficacy,and at the same time,self-illuminates the therapeutic effect in real time is reported here,serving as an ex