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  5. Lipoprotein-like Nanoparticle:Multifunctional Nanoplatform for the Combination Therapy of Alzheimer&

Lipoprotein-like Nanoparticle:Multifunctional Nanoplatform for the Combination Therapy of Alzheimer&

来源 :第三届国际纳米药物大会 ChinaNanomedicine 2018 The 3rd International Con | 被引量 : 0次 | 上传用户：woniu5566
【摘 要】
：
By mimicking high density lipoprotein in the central nervous system(CNS),we constructed discoidal apolipoprotein E3-reconstituted high-density lipoprotein(ApoE3-rHDL)as an efficient nanoplatform that
【作 者】
：
Qingxiang Song Meng Huang Huahua Song Jialin Huang Gan Jiang Lepei Chen Hongzhuan Chen Xiaoling Gao 
【机 构】
：
Department of Pharmacology and Chemical Biology,Faculty of Basic Medicine,Shanghai Jiao Tong Univers
【出 处】
：
第三届国际纳米药物大会 ChinaNanomedicine 2018 The 3rd International Con
【发表日期】
：
2018年7期
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　　By mimicking high density lipoprotein in the central nervous system(CNS),we constructed discoidal apolipoprotein E3-reconstituted high-density lipoprotein(ApoE3-rHDL)as an efficient nanoplatform that could penetrate the blood-brain barrier(BBB)and accelerate Aβ clearance to serve as a novel nanomedicine for the therapy of AD.
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