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  5. Development of benzimidazole derivatives to inhibit HIV-1 replication through protecting APOBEC3G pr

Development of benzimidazole derivatives to inhibit HIV-1 replication through protecting APOBEC3G pr

来源 :2015年全国药物化学学术会议暨第五届中英药物化学学术会议 | 被引量 : 0次 | 上传用户：xinguan701
【摘 要】
：
Human APOBEC3G(apolipoprotein B mRNA-editing enzyme,catalytic polypeptide-like 3G,A3G)is a potent restriction factor against human immunodeficiency virus type 1(HIV-1)by inducing hypermutation of G to
【作 者】
：
Ting Pan Xin He Bing Chen Hui Chen Guannan Geng Haihua Luo Hui Zhang Chuan Bai 
【机 构】
：
Institute of Human Virology
【出 处】
：
2015年全国药物化学学术会议暨第五届中英药物化学学术会议
【发表日期】
：
2015年3期
【关键词】
：
HIV-1 APOBEC3G Vif Benzimidazole 
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　　Human APOBEC3G(apolipoprotein B mRNA-editing enzyme,catalytic polypeptide-like 3G,A3G)is a potent restriction factor against human immunodeficiency virus type 1(HIV-1)by inducing hypermutation of G to A in viral genome after its incorporation into virions.
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