Therapeutic Targets in Gastrointestinal Stromal Tumors

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户:wsdemon8911
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Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumors in the GItract.Gain-of-function mutation in KIT or PDGFRA results in constitutive activation of theprotein tyrosine kinase and its downstream signaling pathways in GIST.
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